Can a AMD Radeon R9 280X run No Man's Sky?

Yes — comfortably

The AMD Radeon R9 280X handles No Man's Sky comfortably — roughly 359 FPS at 1080p and 223 FPS at 1440p on high settings.

359FPS @ 1080p
223FPS @ 1440p
129FPS @ 4K

High preset, upscaling off, paired with a AMD Ryzen 7 9800X3D-class processor.

How the AMD Radeon R9 280X measures up

RequirementAMD Radeon R9 280XMinimumRecommendedResult
GPU performance score 11 2 2 Recommended
Video memory 3 GB 3 GB GB Recommended
Ray tracing — Not supported Game has no RT N/A
Upscaling FSR DLSS, FSR Available

Recommended settings

For 60 FPS at 1080p

Use the ultra preset. You already clear 60 FPS on high, so this leaves headroom for dips in busy scenes.

At 1440p

Comfortable — around 223 FPS on high.

At 4K

Around 129 FPS on high — genuinely viable.

Upscaling

No Man's Sky supports DLSS and FSR. Your card supports FSR — Quality mode is worth 25–40% more frames. Compare upscalers.

How other cards handle No Man's Sky

Graphics cardTier1080p FPSvs AMD Radeon R9 280X
AMD Radeon 890M D 428 ▲ 69 FPS Compare
AMD Radeon RX 6500 XT D 394 ▲ 35 FPS Compare
NVIDIA GeForce GTX 1650 D 359 ▼ 0 FPS Compare
AMD Radeon R9 380X D 359 ▼ 0 FPS Compare
AMD Radeon 780M D 359 ▼ 0 FPS Compare
NVIDIA GeForce GTX 770 D 325 ▼ 34 FPS Compare

Frequently asked questions

Can the AMD Radeon R9 280X run No Man's Sky?

The AMD Radeon R9 280X handles No Man's Sky comfortably — roughly 359 FPS at 1080p and 223 FPS at 1440p on high settings.

What FPS will I get?

On high settings with upscaling off: roughly 359 FPS at 1080p, 223 FPS at 1440p and 129 FPS at 4K. These are modelled estimates — see our methodology.

What settings should I use?

Start at the ultra preset at 1080p. Then enable upscaling on Quality mode before lowering anything further.

Will my processor hold this back?

These figures assume a processor fast enough not to limit the card. If yours is older, run the bottleneck calculator — this title is unusually CPU-heavy, so it matters more than usual here.