Can a AMD Radeon R9 380 run Resident Evil 4?
The AMD Radeon R9 380 falls below the minimum requirement for Resident Evil 4, and its 2GB of VRAM is under the 4GB the game asks for. Expect it to run poorly or refuse to launch.
High preset, upscaling off, paired with a AMD Ryzen 7 9800X3D-class processor.
How the AMD Radeon R9 380 measures up
| Requirement | AMD Radeon R9 380 | Minimum | Recommended | Result |
|---|---|---|---|---|
| GPU performance score | 10 | 7 | 21 | Minimum |
| Video memory | 2 GB | 4 GB | 8 GB | Below |
| Ray tracing | — Not supported | Game supports RT (medium) | N/A | |
| Upscaling | FSR | DLSS, FSR | Available | |
Recommended settings
For 60 FPS at 1080p
Use the low preset. High settings fall short here, so drop the preset before touching resolution.
At 1440p
Around 17 FPS on high — this card is happier at 1080p for this title.
At 4K
Around 10 FPS — not a realistic target for this pairing.
Upscaling
Resident Evil 4 supports DLSS and FSR. Your card supports FSR — Quality mode is worth 25–40% more frames. Compare upscalers.
VRAM headroom
At 2GB you are under the 8GB this game recommends. Lower the texture setting one notch first — it costs the least visual quality per gigabyte saved.
How other cards handle Resident Evil 4
| Graphics card | Tier | 1080p FPS | vs AMD Radeon R9 380 | |
|---|---|---|---|---|
| AMD Radeon R9 380X | D | 30 | ▲ 2 FPS | Compare |
| AMD Radeon R9 280X | D | 30 | ▲ 2 FPS | Compare |
| AMD Radeon 780M | D | 30 | ▲ 2 FPS | Compare |
| NVIDIA GeForce GTX 770 | D | 28 | ▼ 0 FPS | Compare |
| AMD Radeon HD 7970 | D | 28 | ▼ 0 FPS | Compare |
| Intel Arc A380 | D | 28 | ▼ 0 FPS | Compare |
Frequently asked questions
Can the AMD Radeon R9 380 run Resident Evil 4?
The AMD Radeon R9 380 falls below the minimum requirement for Resident Evil 4, and its 2GB of VRAM is under the 4GB the game asks for. Expect it to run poorly or refuse to launch.
What FPS will I get?
On high settings with upscaling off: roughly 28 FPS at 1080p, 17 FPS at 1440p and 10 FPS at 4K. These are modelled estimates — see our methodology.
What settings should I use?
Start at the low preset at 1080p. Then enable upscaling on Quality mode before lowering anything further.
Will my processor hold this back?
These figures assume a processor fast enough not to limit the card. If yours is older, run the bottleneck calculator — this title leans on the GPU, so a modest CPU deficit costs less.